Biofilm control strategies based on the induced disruption of the EPS matrix - a modelling study
Links to animations concerning all the simulations analysed in the article
"Biofilm control strategies based on the induced
disruption of the EPS matrix - a modelling study" are provided here.
Simulations for the undisturbed biofilm growth
Four replicate simulations carried out corresponding to 100 days of undisturbed biofilm growth. Simulations used the same set of parameters with exception of the seed for the random number generator.
|Simulation||Quick Time movie|
Simulations carried out with YEPS* = 1
Simulations of the biofilm being removed in the presence of a PDP (detachment promoting agent). Simulations carried out for diverse values of the Thiele modulus and Damk÷hler number, which quantify the penetration of the PDP into the biofilm and the rate of the EPS reaction relative to the rate of EPS production.
Simulations carried out with variable YEPS*
These simulations also show the biofilm being removed in the presence of a DPA (detachment promoting agent), but these were carried out for diverse values of YEPS*. Values for the Thiele modulus and Damk÷hler number where set at 3.6 and 0.71, respectivelly. Simulation carried out with YEPS* = 1 is simulation T6 shown above.
|Simulation||YEPS*||Quick Time movie|
Simulations for the case where the DPA is involved in a stoichiometric reaction with the EPS
These simulations show the biofilm being removed in the presence of a DPA (detachment promoting agent) for the case where the DPA is involved in a stoichiometric reaction with the EPS. Values for the the Damk÷hler number and YEPS* where set at 0.71 and 1, respectivelly. Simulations shown represent treatments with variable DPA penetration, as quantified by an alternate Thiele modulus (defined in equation 20 in the article).
|Simulation||Thiele modulus||Quick Time movie|
The effect of gamma on biofilm removal
These simulations where caried out using values for gamma ranging from 0.2 to 10. Gamma is the order of the dependence of biofilm cohesiveness on the fraction fEPS (through equation 15 shown in the article). Values for the the Damk÷hler number, Thiele modulus and YEPS* where set at 0.71, 3.6 and 1 respectivelly.
|Simulation||Gamma||Quick Time movie|